Daniel Sinnett has made it his life work to try to save the lives of children and adolescents who have cancer and also prevent survivors from suffering the long-term effects of treatment.

Researchers have identified SLAMF6, an internal brake on the body's immune system that makes cancer spread, and developed antibodies to neutralize it. Promising results have been obtained in mice.

A deeper understanding of immune “brakes” could lead to more effective therapies, according to a study co-authored by UdeM and IRCM researcher André Veillette.